Papillary Mesothelioma
Papillary mesothelioma, known in the medical field as well-differentiated papillary mesothelioma (WDPM), is a rare variant of epithelial mesothelioma. This form of mesothelioma, in contrast with the conventional diffuse malignant mesothelioma (DMM), is considered to be of low malignant potential, or not likely to spread or invade other parts of the body.
Papillary Mesothelioma Treatments
Due to the rare occurrence of this disease, a recommendation of uniform treatment has yet to be established. The typical forms of treatment that have been documented in various studies are similar to traditional mesothelioma treatments and have included surgery and multiple forms of chemotherapy. Patients and their families often have numerous questions about the best way to combat mesothelioma and we offer a comprehensive packet with information about treatment options and top doctors, catered to each patient’s specific diagnosis. Please click here to receive this complimentary packet overnight.
Papillary Mesothelioma Tumors
Well-differentiated papillary mesothelioma tumors typically take an indolent clinical course (meaning the disease causes little to no pain and is relatively inactive and benign) and often bear a good prognosis. However, occasional cases of a more aggressive nature have been reported. In benign papillary mesothelioma instances, high rates of recurrence are relatively common.
Papillary mesothelioma tumors have most commonly developed in the peritoneum of women (usually of reproductive age), which is the mesothelial lining of the abdominal cavity. A number of WDPM cases have also occurred in the tunica vaginalis of the male reproductive system. In addition to these two areas, other cases have been reported in the pericardium (the mesothelial lining of the heart), pleura (the mesothelial lining of the lungs), and ovaries.
Development of Papillary Mesothelioma
Unlike the conclusive relationship between asbestos exposure and DMM, the majority of WDPM cases have developed without any known asbestos exposure. However, a number of patients involved in studies on WDPM have had a history of asbestos exposure ranging from occupational, secondary and household exposure.
Sources:
- Butnor, K., Sporn, T., Hammar, S. et al. Well-Differentiated Papillary Mesothelioma. (2001). The American Journal of Surgical Pathology: 1304-1309.
- Spano, J., Soria, J., Sabourin J. Well-Differentiated Papillary Mesothelioma (WDPM): Successful therapy by local surgery alone or combined with intraoperative intraperitoneal heated chemotherapy (IPHC) perfusion using cisplatin. (2003). Proceeding of the American Society for Clinical Oncology; 22.
- Lovell, F. and Cranston, P. Well-Differentiated Papillary Mesothelioma of the Peritoneum. (1990). American Journal of Roentgenology; 155:66, 1245-1246.
- http://www.ajronline.org/cgi/reprint/155/6/1245.pdf
- McCaughey, D. Well-Differentiated Papillary Mesothelioma of the Peritoneum: a clinicopathologic study of 22 cases. (1990). Cancer; 65: 292-296.
- Hoekstra, A., Riben, M., Frumovitz, M. et al. Well-Differentiated Papillary Mesothelioma of the Peritoneum: a athological analysis and review of the literature. (2005). Gynecologic Oncology; 98(1): 161-167.
Nutrition & Dieting for Cancer
| Learn what foods to eat, which to avoid, and the best supplements for the fight against cancer and chemotherapy recovery. | ![]() ![]() |
Veterans AssistanceAsbestos.com's Veterans Assistance Department can help you with questions about veterans and asbestos-related illnesses or about potential benefits. |
![]() ![]() |
Search through our extensive list of ships that used asbestos-containing products.
(e.g. USS Alabama BB 60)
Mesothelioma BooksTwo must read books for anyone who has or who is caring for someone with mesothelioma. |
![]() ![]() |
Enroll in our Newsletter
Receive a copy of our monthly newsletterwith the latest clinical trials, survivor stories,
doctor profiles, and more.
" Mike Dews, 9-Year Mesothelioma Survivor"
- Mesothelioma Risk Found Among Asbestos Brake and Clutch Manufacturer Workers
03/12/2010 - An article recently published in Regulatory Toxicology and Pharmacology reports on the effects of asbestos exposure among workers in Iran's a.. - Mesothelioma Cancer Takes Life of Pro Football Hall of Famer Merlin Olsen
03/11/2010 - Former National Football League (NFL) player Merlin Olsen passed away on March 10, 2010 at the age of 69 after battling the rare cancer mesothelioma. .. - Mesothelioma Researchers Find Success in Suppressing Growth of Mesothelioma Cells
03/10/2010 - Japanese mesothelioma researchers recently published a study reporting on the success of combining a PLK-1 siRNA with zoledronic acid treatment agains..










